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24 Cards in this Set

  • Front
  • Back
3 major species of Staphylococci
S. aureus
S. epidermidis
S. saprophyticus
how do you differentiate between Staphylococcus and Streptococci
Catalase test
Gram stain
Is Staphylococcus gram +/-?
Gram +
which of the Staphylococci are catalase +
S. aureus
this is diagnostic
which of the Staphylococci are coagulase positive?
S. aureus
If the lab calls you to tell you:
Gram + bacteria
Coagulase +
cocci in clusters
what is your diagnosis?
S. aureus
what are the virulence factors of S. aureus?
Mucopeptide: toxic, antiphagocytic
Coagulase: diagnostic
Cell associated: capsule, protein A, Fibronectin-binding protein, collagen-binding protein, only species with protein A
where does the transmission of S. aureus usually occur?
humans, especially skin, nose, and perineum
what types of disease is caused by S. aureus?
Skin sepsis
Postoperative wound infection
Scalded skin syndrome
Catheter associated infection
Foodborne infection
Toxic Shock Syndrome
True or False
S. aureus is non-fastidious capable of aerobic or anaerobic respiration
how is S. aureus identified in the lab?
white/golden colonies on blood agar
Catalase +
Coagulase +
Most strains ferment MANNITOL anaerobically
what is the action of Protein A in the cell wall of S. aureus?
it is bound to the mucopeptide of the cell wall > interacts with IgG antibodies reducing opsonization and causing local activation of complement
the diseases caused by S. aureus are caused by what?
1. Exotoxin release
2. Direct organ invasion
what are the diseases caused by S. aureus exotoxin release?
1. Gastroenteritis
2. Toxic Shock Syndrome
3. Scalded skin syndrome
what are the diseases caused by S. aureus direct organ invasion?
1. pneumonia
2. meningitis
3. osteomyelitis
4. acute bacterial endocarditis
5. septic arthritis
6. bacteremia/sepsis
7. skin infections
8. urinary tract infections
what is the drug of choice for treatment of MRSA?
how is S. epidermis identified clinically?
white colonies on blood agar
Catalase +
Coagulase -
Mannitol not fermented anaerobically
what type of disease is caused by S. epidermis?
opportunist pathogen associated with device related sepsis
what are some specific diseases caused by S. epidermis?
catheter related sepsis
Prosthetic valve endocarditis
infection of artificial joint
shunt infections
Sternal wound osteomyelitis
Is S. epidermis coagulase negative/positive
this is differential diagnostic between S. aureus & S. epidermis
what may assist S. epidermis in colonization of plastic implants?
extracellular slime production
Is Staph Saprophyticus part of the normal flora of humans.
what microbe is the leading cause of UTI in sexually active women?
Staph. Saprophyticus
How is S. Saprophyticus differentiated from S. epidermidis?
S. Saprophyticus is Catalase - and Coagulase -
S. epidermidis is Catalse + and Coagulase -