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37 Cards in this Set

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Eccrine glands are found where?

Everywhere EXCEPT:



ears and lips!!! external auditory canal, lips, clitoris, labia minora/glans penis

Apocrine glands are distributed where?

Molly's mom needs to bring her eyes and ears to the PTA meeting...



eyelids (Moll's glands)


EAC (cerumin glands)


PITS


TITTS


ASS

Sebaceous glands are distributed where?

everywhere but palms and soles

Meibomian glands?

sebaceous glands of tarsal plate



remember Zeis (sebaceous glands on superficial eyelid) goes BOOM (meibomian glands)

Montgomery tubercles?

Sebaceous glands on nipple and areola

Tyson's glands?

sebaceous glands of gland penis/labia minora

Fordyce spots?

sebaceous glands on vermillion border of lips, labia majora, penile shaft

Gland of Zeis?

Sebaceous glands on superficial eyelid



Zeis goes BOOM (mebomian glands on eye)

Study showed that 21% of women with LSA also had an autoimmune disease...

MC thyroid (12%), AA (9%), vitiligo (2%)

Antibodies to ECM-1? Loss of function of ECM-1?

Autoantibodies: LSA



LOF: lipoid proteinosis

MC location of LSA?

85% genital

Clinical distinction between LSA and vaginal LP?

LSA does NOT involve vagina or cervix, vaginal LP does

What is delling?

white-brown follicular plugs, seen in LSA

Risk of SCC with LSA?

In women, slightly increased risk, <5%



In men, 25-50% of penile SCC are preceded by LS

treatment?

treatment?

balanitis xerotica obliterans



ultra potent topical steroids

What are the 4 types of genital LP? Which is most common in women?

papules/plaque



hypertrophic



erosive- MC in women



LPP

What type of LP is associated with hepatitis C?

erosive oral LP

genital LP has an associated increased risk of what?

SCC

Treatment for LP?

topical steroids



LP less likely to remit than LSA

cure?

cure?

Zoon's balanitis, usually seen in uncircumsized men d/t poor hygiene and chronic irritation



erythematous, moist plaques with cayenne pepper speckled appearance and orange hue



circumcision = cure

disease?

disease?

Circinate balanitis is the dermatologic manifestation of reactive arthritis

Characteristics of reactive arthritis? Derm findings?

Arthritis, urethritis, conjunctivitis
 
circinate balanitis- serpiginous dermatitis of penis
 
keratoderma blenorrhagicum- foot

Arthritis, urethritis, conjunctivitis



circinate balanitis- serpiginous dermatitis of penis



keratoderma blenorrhagicum- foot

MCC of genital fixed drug eruption?

bactrim

MCC of lip (mouth) fixed drug eruption?

NSAIDS (pyrazolone derivatives)

what is this?

what is this?

Chronic bullous disease of childhood (linear IgA)



genital involvement is common especially in kids

gene defect?

gene defect?

Angiokeratomas in a bathing suit distribution --> Fabry's disease



XLR



GLA gene (alpha galactosidase A) --> accumulation of glycosphingolipids in vascular endothelial tissue

extracutaneous features associated?

extracutaneous features associated?

Angiokeratomas in a bathing suit distribution --> Fabry's disease



XLR



GLA gene (alpha galactosidase A) --> accumulation of glycosphingolipids in vascular endothelial tissue



cardiac disease with abnormal EKG and MI, renal disease with maltese cross (lipids in urine), corneal opacities

Which genoderm can have verruciform xanthoma-like changes within its epidermal nevi?

CHILD syndrome (congenital hemidysplasia, ichthyosiform erythroderma and Limb defects



XLD defect in NSDHL gene (cholesterol metabolism)



no CHILD in the NHL

lesion on labia majora?

lesion on labia majora?

hidradenoma papilliferum

HPV associated with genital neoplasia?

HPV 16, 18, 31, 33

What are the 4 types of extramammary paget's?

1. primary EMPD- arises intraepidermally from Toker cells= apocrine stem cells in skin)



2. extension of underlying adnexal carcinoma



3. a/w underlying adjacent visceral malignancy



4. a/w underlying distant carcinoma

Presentation?

Presentation?

perioral and genital dermatitis after weaning from breast feeding (breastmilk has adequate and accessible zinc)

What is the defect?

What is the defect?

SLC39A4



Acrodermatitis enteropathica

What is the staining pattern for langerhans cells?

Cd1a+, S100+, Langerin +

Criteria for Bechet's disease?

recurrent oral ulcers >3 in 1 year, plus any 2 of the following:



recurrent genital ulcers



ocular findings (uveitis, retinal vasculitis)



cutaneous lesions (EN)



positive pathergy test

Cause of perianal strep?

group A B hemolytic strep (pyogenes)

fluoresces with a woods lamp?

fluoresces with a woods lamp?

erythrasma



coral red d/t coproporphyrin III



corynebacterium minutissimum